As our earliest ancestors migrated out of Africa, they encountered entirely new floras. By sampling these, they found plants that appeared to (and sometimes did) heal wounds, cure maladies, and ease troubled minds. This process of discovery continues today, as multinational pharmaceutical companies bioprospect in the globe's remaining wild places for the next tamoxifen or digitalis.

The gardener and botanist David Stuart tells the fascinating story of botanical medicine, revealing more than soothing balms and heroic cures. Most of the truly powerful and effective medicinal plants are double-edged, with a dark side to balance the light. They can heal or kill, calm or enslave, lift depression or summon our gods and monsters. Often the difference between these polar effects is a simple change in dosage.

Stuart chronicles the tale of how the herbal materia medica of healing and killing plants has sparked wars, helped establish intercontinental trade routes, and seeded fortunes. As plant species traveled the globe, their medicinal uses evolved over miles and through centuries. Plants once believed to be cure-alls are now considered too dangerous for use. Others, once so valuable that they sowed the wealth of empires, are merely spices on the kitchen shelf.

David Stuart recounts engrossing human stories too, not only of the scientists, explorers, and doctors who gathered, named, and prescribed these plants but also the shamans, magicians, and quacks who claimed to possess the ultimate herbal aphrodisiac or elixir.

For 1,600 years Dioscorides (ca. AD 40–80) was regarded as the foremost authority on drugs. He knew mild laxatives and strong purgatives, analgesics for headaches, antiseptics for wounds, emetics to rid one of ingested poisons, chemotherapy agents for cancer treatments, and even oral contraceptives. Why, then, have his works remained obscure in recent centuries? Because of one small oversight (Dioscorides himself thought it was self-evident): he failed to describe his method for organizing drugs by their affinities. This omission led medical authorities to use his materials as a guide to pharmacy while overlooking Dioscorides' most valuable contribution—his empirically derived method for observing and classifying drugs by clinical testing.

Dioscorides' De materia medica, a five-volume work, was written in the first century. Here revealed for the first time is the thesis that Dioscorides wrote more than a lengthy guide book. He wrote a great work of science. He had said that he discovered the natural order and would demonstrate it by his arrangement of drugs from plants, minerals, and animals. Until John M. Riddle's pathfinding study, no one saw the genius of his system. Botanists from the eighteenth century often attempted to find his unexplained method by identifying the sequences of his plants according to the Linnean system but, while there are certain patterns, there remained inexplicable incoherencies. However, Dioscorides' natural order as set down in De materia medica was determined by drug affinities as detected by his acute, clinical ability to observe drug reactions in and on the body. So remarkable was his ability to see relationships that, in some cases, he saw what we know to be common chemicals shared by plants of the same and related species and other natural product drugs from animal and mineral sources.

Western European and Islamic medicine considered Dioscorides the foremost authority on drugs, just as Hippocrates is regarded as the Father of Medicine. They saw him point the way but only described the end of his finger, despite the fact that in the sixteenth century alone there were over one hundred books published on him. If he had explained what he thought to be self-evident, then science, especially chemistry and medicine, would almost certainly have developed differently. In this culmination of over twenty years of research, Riddle employs modern science and anthropological studies innovatively and cautiously to demonstrate the substance to Dioscorides' authority in medicine.

The medicinal properties of plants have been of interest to society for centuries and continue to be a subject of modern research. Yet too often research has been predicated upon poorly identified plant material and secondary sources of information. Much of what we know about the use of plants as drugs, poisons, foods, and as instruments of magical or religious practice derives from lore inherited from the clay tablets and papyri of the ancients and from compilations of early Greek, Arabic, and Indian physicians. Meanwhile, information pertaining to plant parts used even now in the daily life of peoples far removed from the influence of modern medical and health practices has been largely overlooked.

With the encroachment of civilized cultures on primitive societies, unique traditions—often unwritten—are being destroyed. In many instances, the very plants involved are disappearing. Not infrequently, the only record, where one exists at all, of these vanishing pools of knowledge is that of the botanical field worker. For no matter what chemical or biological investigations may follow, the botanist can affix to an actual specimen, as he collects it in the field, the local terms applied to the plant and a description of native medicinal or other uses.

Dr. Altschul has compiled field notes of health and medical interest on over 5,000 species of plants, culled from some 2,500,000 specimens of higher plants collected by field botanists from all over the world and deposited in the combined collections of the Arnold Arboretum and Gray Herbarium of Harvard University. The resulting catalogue represents a unique approach to supplying new investigational leads to researchers seeking biologically active plant principles. Dr. Altschul's meticulous sheet&ndashby–sheet examination of the Harvard collections provides the pharmacognosist, pharmacologist, and others in the medical and health sciences with an extensive firsthand survey of the domestic medicines of many cultures.

These previously unpublished botanists' notes are here made available in a comprehensive publication that should become an important resource for every investigation into the area of medicinal phytochemistry. Indexes to families and genera are provided, as well as a medical index referring to diseases and to therapeutic properties for researchers intent on locating plants with special medicinal capacities. The author is a Research Fellow at the Botanical Museum of Harvard University.

This companion volume to Siri von Reis's previous exploration of ethnobotanical notes in the Harvard herbaria brings to light a new array of plants with drug or food potential, offering wide-ranging possible applications for pharmacologists, chemists, botanists, and even anthropologists. Following the same criteria as in earlier investigations, the authors have examined the vast holdings of The New York Botanical Garden Herbarium to select little-known plant uses and to record any note suggesting biodynamic constituents--i.e., those having effects on living tissue--from skin irritants and poisons and medications of any kind to foods, beverages, and spices. They have also included species whose applications suggest other kinds of unreported chemical activity, plants associated with magic or ritual which affected people in some unusual way.

Listing the notes in the order in which the species were found in the collection, family by family, the authors call attention to similar characteristics in related species and families having biodvnamic properties in common. Each entry begins with the Latin name of the specimen, cites the country in which it was collected, the collector's name, and his held number for the plant, and then quotes the ethnobotanical or other note of interest.

While in itself a valuable reference work in the search for clues to useful plants, New Plant Source for Drugs and Foods also will enhance the value of the first volume by allowing a comparison of entries.

When workmen excavating the ruins of Pompeii eagerly gathered the native medicinal plants growing there, Wilhelmina Jashemski discovered that this was another example of the continuity of life in the shadow of Vesuvius. Many of the plants used for herbal medicine around Pompeii today are the same ones that ancient authorities such as Pliny the Elder and Dioscorides recommended for treating the same types of disorders.

In this book, Jashemski presents an herbal of thirty-six medicinal plants, most of them known to the ancients and still employed today. She describes each plant's contemporary medicinal uses and compares them to ancient practices as recorded in literary sources. Scientific, English, and Italian names and the plant's mythological associations complete the entries, while elegant, full-page portraits depict each plant visually.